Synthetic Biologics

Tissue Scaffolds and Regenerative Materials:

• Description: These are engineered structures, often made from biodegradable synthetic polymers (like PCL, PLA, PLGA) or composites combining synthetic and natural materials (like collagen, hyaluronic acid). They are designed to provide temporary physical support while encouraging the patient’s own cells to infiltrate, grow, and regenerate new tissue (e.g., bone, cartilage, skin).
• Synthetic Biology Aspect: The design often involves precise control over architecture (pore size, interconnectivity), degradation rate, surface chemistry (to promote cell adhesion), and sometimes the incorporation of signaling molecules or growth factors (which might themselves be produced via recombinant DNA technology).
• Surgical Use: Orthopedic repair (bone voids), cartilage repair, wound healing, nerve regeneration conduits